Description
Product Description:
MT-2 is a cyclic heptapeptide analog of the endogenous hormone alpha-MSH. In specialized research settings, it is studied for its ability to non-selectively mimic the effects of melanocortins—peptides fundamentally involved in the regulation of several physiological functions, most notably skin pigmentation, cellular photoprotection, and energy homeostasis.
Unlike natural alpha-MSH, MT-2 features a structurally modified sequence that grants it a significantly longer biological half-life and greater metabolic potency. Researchers utilize this compound to map and analyze the activation of the Melanocortin 1 (MC1R), 3 (MC3R), and 4 (MC4R) receptors. By target-stimulating these pathways in controlled models, scientists can observe and measure the induction of melanogenesis—the biochemical process by which melanocytes produce melanin—completely independent of direct UV radiation exposure.
Our MT-2 is synthesized to a 99% purity standard and supplied as a precise 10mg total weight vial, ensuring the absolute chemical stability and baseline consistency required for repeatable, high-integrity laboratory data.
Prominent Areas of MOTS-c Research
In preclinical and laboratory studies, MT-2 is a primary subject of interest across several specialized research domains:
- Melanogenesis & Skin Pigmentation: The most prominent area of study involves MT-2’s role in stimulating the MC1 receptor to induce systemic melanin production. Researchers use this to investigate how increased melanin levels affect dermal appearance and cellular response in animal models.
- Photoprotection & UV Response: Studies explore the potential of MT-2 to provide “internal” photoprotection. Researchers investigate whether the induction of eumelanin (darker pigment) can mitigate DNA damage and oxidative stress typically caused by ultraviolet radiation.
- Systemic Melanocortin Signaling: Beyond pigmentation, MT-2 is studied for its interaction with the MC4 receptor, which is involved in appetite regulation, energy expenditure, and sexual signaling. This makes it a versatile subject for metabolic and behavioral research.
- Inflammatory Response Modulation: Some research focuses on the anti-inflammatory properties of melanocortin agonists and how compounds like MT-2 might influence the immune signaling environment within skin tissues.
LABORATORY USE DISCLAIMER
This product (MT-2 / Melanotan II) is sold strictly for research and laboratory purposes only. It is not intended for human consumption, medical diagnosis, therapeutic use, or any form of cosmetic application (including self-tanning). All potential “effects” mentioned are areas of scientific investigation within controlled, approved preclinical or in-vitro settings and have not been validated by the FDA for human use. Proper laboratory safety and handling protocols are required.
